Treatment of Myopia with Atropine 0.125% Once Every Night Compared with Atropine 0.125% Every Other Night: A Pilot Study

(1) Purpose: To investigate the efficacy of myopia treatment in children using atropine 0.125% once every two nights (QON) compared with night (HS). (2) Methods: This retrospective cohort study reviewed medical records groups myopia. Group 1 comprised treated QON, while group 2 included HS. The first 6 months data outcome measurements were subtracted as washout periods those undergoing both QON and HS treatment. independent t-test Pearson’s chi-square test used to compare baseline clinical characteristics between groups. A generalized estimating equations (GEE) model was determine factors that influence effects. (3) Results: average ages (38 eyes from 19 patients) (130 65 10.6 10.2 years, respectively. There no significant differences axial length (AL) or cycloplegic spherical equivalent (SEq) at changes them after 16.9 follow-up. GEE showed frequency use has association annual AL (QON vs. HS: 0.16 ± 0.10 0.18 0.12) SEq −0.29 0.44 −0.34 0.36) all It also older age (B = −0.020, p < 0.001) associated lesser elongation. (4) Conclusion: effects similar this pilot study. may be an alternative strategy for who cannot tolerate side observation should confirmed further large-scale studies.